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Sildenafil
Clinical data
Pronunciation	/ s ɪ l ˈ d ɛ n ə f ɪ l / sil- DEN -ə-fil
Trade names	Viagra, Revatio, others
AHFS/Drugs.com	Monograph
MedlinePlus	a699015
License data	EU EMA: by INN, US FDA: Sildenafil
Pregnancy category	AU: B1 US: B (No risk in non-human studies)
Routes of administration	By mouth (tablets), IV
ATC code	G04BE03 ( WHO )
Legal status
Legal status	AU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	41% (mean) [1]
Protein binding	~96%
Metabolism	Liver: CYP3A4 (major route), CYP2C9 (minor route)
Metabolites	N -desmethylsildenafil (~50% potency for PDE 5 )
Elimination half-life	3–4 hours
Excretion	Feces (~80%), urine (~13%) [2]

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Please be notified that EMS is unavailable in several countries. Manufacturers of generic drugs cannot use brand names on their pharmaceuticals as that would be the breach of copyright while using the well known ingredients is absolutely legal.

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