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It is not effective for dissolving calcified gallstones or pigment gallstones.Its structure is shown below.
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World J Gastroenterol.3 4 UDCA helps reduce the cholesterol saturation of bile and leads to gradual dissolution of cholesterol-rich gallstones.
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And 1000 mg/kg/day. It was not tumorigenic in mice.Unabsorbed ursodiol reaches the colon unchanged, where it is primarily 7-dehydroxylated to form lithocholic acid.
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